FORMULASI GAMEKSAN
DALAM
BENTUK MIKROEMULSI
ABSTRACT
The clinical use of the poorly water-soluble drug substance
become inefficient by means of low level penetration of such kind drug in the
body. Microemulsion is a dispersion system like an emulsion which could help to
increase the solubility of poorly water-soluble drug. In this research, poorly
water-soluble drug is made in a dosage form of microemulsion with Gamexan as a
model. An experiment has been conduct by using benzyl benzoate as an oil phase,
Tween 20 with variety concentration (35%;40%;45%) and sodium lauryl ether
sulphate as surfactant components. The evaluation are consist of determining
the amount of Gamexan in the microemulsion and stability test both physic and
chemically. The result shows that all three of the microemulsion formula dosage
form indicate good stability during two months of storing.
Key words : microemulsion, Gamexan, surfactant.
Link Downlaod: Gas Spektrofotometry.doc
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